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Chemical Name: Palmitoylethanolamide; N-(2-Hydroxyethyl)hexadecanamide; PEA; Palmidrol
CAS NO: 544-31-0
Molecular formula: C18H37NO2
Molecular weight 299.49
Appearance: White powder
Content: 98%
Palmitoylethanolamide Typical Properties
| Item |
Specifications |
| Active Ingredients |
| Assay(%, On Dried base) |
NLT98.0% |
| Physical Control |
| Appearance |
Fine Powder |
| Color |
White to Off-White |
| Identification |
Positive |
| Loss on Drying |
1.0% Max |
| Residue on ignition |
0.1% Max |
| Particle size |
D(0.5): 3μm |
| D(0.99): 10μm |
| Excipients |
None |
| Chemical Control |
| Heavy Metals |
NMT10 ppm |
| Lead(Pb) |
NMT1ppm |
| Sulfate(SO4) |
NMT0.040% |
| Chloride(Cl) |
NMT0.020% |
| Solvent Residual |
Meeting USP Standard |
| Microbiological Control |
| Total Plate Count |
10,000cfu/g Max |
| Yeast Mold |
300cfu/g Max |
| Coliforms |
10cfu/g Max |
| E.Coli |
Negative/10g |
| Salmonella sp. |
Negative/25g |
| Staph Aureus |
Negative/10g |
| Pseudomonas aeruginosa |
Negative/25g |
Hint
The palmitoylethanolamide produced by our company is directly edible and is often used as a raw material for food additives.
PalmitoylethanolamideApplication
1. has anti-inflammatory, anti-injury, mainly in food, health care products additives.
2. used in drugs mainly play a neuroprotective, and anti-convulsive nature.
what is palmitoylethanolamide
1. Palmitoylethanolamide is an endogenous fatty acid amide belonging to the class of nuclear transcription factor agonists. PEA has been shown to bind to nuclear receptors in the nucleus and is a natural anti-inflammatory agent for the generation and marketing of a variety of chronic pain and inflammation-related biological functions.
2. PPAR-α, a member of the peroxide proliferator-activated receptor PPARs, the other two subtypes are PPAR-β and PPARγ. PPAR-α is mainly distributed in some organs and tissues with active catabolism of fat. It is the main transcriptional regulator of fatty acid oxidase gene, which is involved in mediating lipid uptake and oxidation, and mediating amino acid metabolism. From a macroscopic point of view, it can participate in hemostasis, inflammation, lipid metabolism disorder, atherosclerosis and coronary heart disease. a pharmacological and physiological process.
3. In the animal experiments of chronic pain and inflammation models, the mechanism of action and the effect of PEA have been further verified.
4. In the model of chronic granulomatosis pain, PEA can prevent mechanical pain caused by nerve formation and germination. PEA can also inhibit the activation of ganglia, which indicates that PEA is an analgesic and anti-inflammatory substance. It is based on different mechanisms of action.
5. In the nervous system, PEA is produced as a result of the repair mechanism of chronic inflammation and chronic pain in the body. In bladder inflammation, PEA can attenuate the pain caused by visceral nerve reflexes. In the femoral nervous system, PEA achieves the effect of reducing pain perception by affecting the peripheral mast cells that promote inflammation.
PalmitoylethanolamidePacking and Storage
Packing Pack in paper-drums and two plastic bags inside. 25 Kg/Drum
PalmitoylethanolamideStorage
Store in a well-closed container away from moisture and direct sunlight. |
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